INT124870

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Context Info
Confidence 0.57
First Reported 2004
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (SDHAF2) nucleolus (SDHAF2) nucleus (SDHAF2)
cytoplasm (SDHAF2)
Anatomy Link Frequency
platelet 3
SDHAF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 6 67.12 Quite High
headache 4 25.00 Low Low
positron emission tomography 4 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Catecholamine 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 6 98.24 Very High Very High Very High
Paraganglioma 59 96.56 Very High Very High Very High
Ataxia 1 95.24 Very High Very High Very High
Muscle Disease 1 94.80 High High
Frailty 1 93.56 High High
Disease 15 92.16 High High
Malignant Neoplastic Disease 5 71.96 Quite High
Cancer 23 39.52 Quite Low
Genetic Predisposition To Disease 4 32.08 Quite Low
Pulmonary Disease 1 20.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This double-blinded, randomized, placebo-controlled study was undertaken to investigate whether D-003 (20 mg/day) modifies serum levels of TxB2 and Pgl2 and inhibits platelet aggregation in human healthy volunteers.
Gene_expression (levels) of Pgl2 in platelet
1) Confidence 0.57 Published 2004 Journal Int J Clin Pharmacol Res Section Abstract Doc Link 15689052 Disease Relevance 0 Pain Relevance 0
We conclude that D-003 at 20 mg/day for 14 days significantly inhibited platelet aggregation to AA and collagen and reduced TxB2 and increased Pgl2 serum levels.
Gene_expression (levels) of Pgl2 in platelet
2) Confidence 0.57 Published 2004 Journal Int J Clin Pharmacol Res Section Abstract Doc Link 15689052 Disease Relevance 0 Pain Relevance 0
Serum levels of TxB2 and Pgl2 and platelet aggregation to arachidonic acid (AA) (1.75 mM) and collagen (1 microg/ml) were assessed.
Gene_expression (levels) of Pgl2 in platelet
3) Confidence 0.57 Published 2004 Journal Int J Clin Pharmacol Res Section Abstract Doc Link 15689052 Disease Relevance 0 Pain Relevance 0
The PGL2 gene
Gene_expression (The) of PGL2 gene
4) Confidence 0.07 Published 2006 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2837305 Disease Relevance 1.37 Pain Relevance 0.03

General Comments

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