INT124875

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.18
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (FOS) aging (FOS) nucleolus (FOS)
nucleus (FOS)
Anatomy Link Frequency
neuronal 2
TNC 2
FOS (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 2 99.28 Very High Very High Very High
fifth nerve 4 97.96 Very High Very High Very High
neuropeptide release 1 88.52 High High
qutenza 7 85.20 High High
cerebral cortex 1 71.92 Quite High
midbrain 2 23.60 Low Low
gABA 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Deafferentation 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 2 99.28 Very High Very High Very High
Anxiety Disorder 1 85.16 High High
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We examined the effects of a 30 min NO-donor infusion on CGRP release in jugular vein blood and c-fos LI within TNC of the rat.
Spec (examined) Regulation (effects) of Localization (release) of c-fos in TNC
1) Confidence 0.44 Published 2005 Journal Cephalalgia Section Abstract Doc Link 15689199 Disease Relevance 0.10 Pain Relevance 0.51
It is known that c-fos accumulation in nuclei depends on intracellular Ca2+ and second messenger increases as a consequence of changes in neuronal activity (Morgan and Curran, 1988; Sheng and Greenberg, 1990).
Regulation (depends) of Localization (accumulation) of c-fos in neuronal
2) Confidence 0.44 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2981384 Disease Relevance 0.09 Pain Relevance 0.04

General Comments

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