INT124986

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Context Info
Confidence 0.50
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.22
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Rac1) enzyme binding (Rac1) GTPase activity (Rac1)
cytoplasm (Rac1) cell proliferation (Rac1) cell motility (Rac1)
Anatomy Link Frequency
bladder 4
Rac1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
c fibre 2 94.56 High High
Sciatica 6 10.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 100.00 Very High Very High Very High
Overactive Bladder 8 99.60 Very High Very High Very High
Shock 2 92.68 High High
Movement Disorders 6 61.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cystometry revealed that cyclophosphamide and botulinum toxin A treatments altered non-voiding (i.e. cyclophosphamide increased, botulinum toxin A decreased) but not voiding contraction frequency suggesting that alterations in urothelial ATP release selectively diminished underlying bladder C-fiber nerve activity.
Positive_regulation (increased) of Localization (decreased) of botulinum toxin in bladder associated with c fibre and overactive bladder
1) Confidence 0.50 Published 2005 Journal Neurochem. Int. Section Abstract Doc Link 15970360 Disease Relevance 0.62 Pain Relevance 0.18
Enhanced ATP release from rat bladder urothelium during chronic bladder inflammation: effect of botulinum toxin A.
Positive_regulation (Enhanced) of Localization (release) of botulinum toxin in bladder associated with inflammation
2) Confidence 0.50 Published 2005 Journal Neurochem. Int. Section Title Doc Link 15970360 Disease Relevance 0.48 Pain Relevance 0.14
Perioperative use of botulinum toxin and halo vest immobilization can increase the rate of clinical success but requires vigilance to minimize complications.
Positive_regulation (increase) of Localization (use) of botulinum toxin
3) Confidence 0.04 Published 2005 Journal J Spinal Disord Tech Section Body Doc Link 15699795 Disease Relevance 0.06 Pain Relevance 0
Perioperative use of botulinum toxin and halo vest immobilization can increase the rate of clinical success but requires vigilance to minimize complications.
Positive_regulation (requires) of Localization (use) of botulinum toxin
4) Confidence 0.04 Published 2005 Journal J Spinal Disord Tech Section Body Doc Link 15699795 Disease Relevance 0.06 Pain Relevance 0

General Comments

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