INT125000

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Esr1, Tas2r108) cilium (Tas2r108) enzyme binding (Esr1)
DNA binding (Esr1) protein complex (Esr1) signal transducer activity (Tas2r108)
Esr1 (Mus musculus)
Tas2r108 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 81.60 Quite High
headache 1 58.40 Quite High
Disease Link Frequency Relevance Heat
Breast Cancer 1 96.76 Very High Very High Very High
Hot Flashes 1 59.44 Quite High
Headache 1 58.40 Quite High
Vomiting 2 57.28 Quite High
Disease 1 45.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TAS-108 is a novel steroidal antiestrogen compound that has a strong binding affinity to the estrogen receptor and, in preclinical studies, has antitumor activity against tamoxifen-resistant breast cancer cell lines.
estrogen receptor Binding (affinity) of TAS-108 associated with breast cancer
1) Confidence 0.04 Published 2005 Journal Clin. Cancer Res. Section Abstract Doc Link 15701885 Disease Relevance 0.33 Pain Relevance 0.10

General Comments

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