INT125009

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.22
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (HDAC5) nucleolus (HDAC5) nucleus (HDAC5)
transcription factor binding (HDAC5) cytoplasm (HDAC5)
Anatomy Link Frequency
leukocyte 2
Paneth cells 1
HDAC5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 27 65.72 Quite High
fibrosis 1 50.04 Quite High
peptic ulcer disease 2 50.00 Quite Low
psoriasis 1 48.48 Quite Low
Crohn's disease 20 45.60 Quite Low
Bile 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 20 66.32 Quite High
INFLAMMATION 23 57.04 Quite High
Otitis Media 1 50.72 Quite High
Cystic Fibrosis 1 50.04 Quite High
Disease 30 50.00 Quite Low
Ulcers 2 50.00 Quite Low
Eczema 1 49.36 Quite Low
Psoriasis 1 48.48 Quite Low
Neonatal Necrotizing Enterocolitis 1 46.92 Quite Low
Sprains And Strains 3 5.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: We assessed the expression of epithelial secretory leukocyte protease inhibitor, human beta-defensins (HBD1 and HBD2), and alpha-defensin (HD5) in gastric biopsies taken from 52 patients, median age of 55 years.
Gene_expression (expression) of HD5 in leukocyte
1) Confidence 0.44 Published 2005 Journal Dig Liver Dis Section Body Doc Link 15702860 Disease Relevance 0 Pain Relevance 0
The intake of aspirin by patients infected with H. pylori was associated with marked rise in the expression of HD5 and less expression of secretory leukocyte protease inhibitor.
Gene_expression (expression) of HD5 in leukocyte
2) Confidence 0.34 Published 2005 Journal Dig Liver Dis Section Body Doc Link 15702860 Disease Relevance 0 Pain Relevance 0
-defensins includes human neutrophil peptides 1–4 (HNP1–4) produced by granulocytes and human defensin 5 and 6 (HD5 and HD6) produced by Paneth cells.
Gene_expression (produced) of HD5 in Paneth cells
3) Confidence 0.15 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2992817 Disease Relevance 0.22 Pain Relevance 0.09

General Comments

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