INT125096

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NEU2) small molecule metabolic process (NEU2) hydrolase activity, acting on glycosyl bonds (NEU2)
cytoplasm (NEU2)
NEU2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 70.32 Quite High
TRP channel 1 68.72 Quite High
Glutamate 46 5.00 Very Low Very Low Very Low
Neurotransmitter 15 5.00 Very Low Very Low Very Low
gABA 14 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 1 70.32 Quite High
Stress 5 68.48 Quite High
Hypoxia 33 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Neurological Disease 3 5.00 Very Low Very Low Very Low
Cerebral Hypoxia 3 5.00 Very Low Very Low Very Low
Metabolic Disorder 2 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Maple Syrup Urine Disease 1 5.00 Very Low Very Low Very Low
Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Truncation of TRPV1, expression of cytosolic termini of TRPV1 or TRPV4 and construction of chimeric TRPV channel subunits revealed that the specificity and the affinity of the subunit interaction is synergistically provided by interaction modules located in the transmembrane domains and in the cytosolic termini.
Gene_expression (expression) of cytosolic
1) Confidence 0.03 Published 2005 Journal J. Cell. Sci. Section Abstract Doc Link 15713749 Disease Relevance 0.07 Pain Relevance 0.10
Therefore, the dehydrogenation reaction in astrocytic mitochondria was added to the model in reverse direction (r151), allowing the transfer of cytosolic NADH to mitochondria in the form of FADH2.
Gene_expression (transfer) of cytosolic
2) Confidence 0.01 Published 2007 Journal Theor Biol Med Model Section Body Doc Link PMC2246127 Disease Relevance 0.07 Pain Relevance 0

General Comments

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