INT125446

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Context Info
Confidence 0.59
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.14
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (CLDN4) plasma membrane (CLDN4)
CLDN4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 5 99.16 Very High Very High Very High
spastic colon 71 95.92 Very High Very High Very High
Inflammation 7 91.60 High High
cINOD 8 89.24 High High
diclofenac 1 86.64 High High
Pain 1 31.68 Quite Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 13 98.84 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

68 95.92 Very High Very High Very High
Inflammatory Bowel Disease 71 93.00 High High
INFLAMMATION 9 91.60 High High
Alagille Syndrome 3 85.52 High High
Recurrence 1 83.92 Quite High
Apoptosis 1 80.96 Quite High
Stomach Cancer 1 75.28 Quite High
Food Poisoning 1 65.16 Quite High
Colitis 5 63.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, an intracellular Ca2+ chelator [1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid] inhibited the indomethacin-dependent induction of claudin-4.
Negative_regulation (inhibited) of Positive_regulation (induction) of claudin-4
1) Confidence 0.59 Published 2005 Journal Cancer Res. Section Abstract Doc Link 15753385 Disease Relevance 0.51 Pain Relevance 0.49
A number of publications have reported a decrease of bacteria belonging to the groups Clostridium XIVa and Clostridium IV in patients with Crohn's disease (CD), [18-20].
Negative_regulation (decrease) of Positive_regulation (groups) of Clostridium associated with crohn's disease and disease
2) Confidence 0.03 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC3002299 Disease Relevance 1.09 Pain Relevance 0.80

General Comments

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