INT125476

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2008
Negated 0
Speculated 2
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 1.10
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (HHIP) plasma membrane (HHIP) carbohydrate metabolic process (HHIP)
cytoplasm (HHIP)
Anatomy Link Frequency
Hip 4
embryonic kidney 2
HHIP (Homo sapiens)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 37 100.00 Very High Very High Very High
Chronic pancreatitis 7 99.50 Very High Very High Very High
agonist 530 97.28 Very High Very High Very High
Hippocampus 3 69.36 Quite High
Electroencephalography 9 57.24 Quite High
imagery 36 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
dopamine receptor 5 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 8 99.68 Very High Very High Very High
Disease 6 99.60 Very High Very High Very High
Pancreatitis 7 99.50 Very High Very High Very High
Pancreatic Cancer 5 82.56 Quite High
Cognitive Disorder 6 71.12 Quite High
Glioma 1 50.96 Quite High
Malignant Neoplastic Disease 1 25.00 Low Low
Cv Unclassified Under Development 15 5.00 Very Low Very Low Very Low
Stroke 15 5.00 Very Low Very Low Very Low
Thrombosis 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The different pattern of Hip expression and abnormal localization in the diseased pancreas suggest that the enhanced activation of hedgehog signaling in CP and PDAC is-at least in part-due to the aberrant responsiveness and expression of Hip in these diseases.
Regulation (part-due) of Gene_expression (expression) of Hip in Hip associated with adenocarcinoma, disease and chronic pancreatitis
1) Confidence 0.39 Published 2005 Journal Mol. Carcinog. Section Abstract Doc Link 15754313 Disease Relevance 1.02 Pain Relevance 0.26
Possible involvement of the ACC and Hip activities in generating the P300
Spec (Possible) Regulation (involvement) of Gene_expression (activities) of Hip in Hip associated with anterior cingulate cortex
2) Confidence 0.38 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2607283 Disease Relevance 0.07 Pain Relevance 0.20
In order to monitor changes in cell-surface expression of the hIP as a function of cicaprost-stimulation and/or colocalization with Rab5, HEK.hIP cells were transiently transfected with 10 ?
Regulation (changes) of Gene_expression (expression) of hIP
3) Confidence 0.06 Published 2008 Journal Biochim Biophys Acta Section Body Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.05
These data confirm that both the wild type hIP and its truncated variants hIP?
Regulation (truncated) of Gene_expression (variants) of hIP
4) Confidence 0.04 Published 2008 Journal Biochim Biophys Acta Section Body Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.15
Specifically, cell surface HA-tagged receptors in HEK.hIP cells were initially pre-immunolabelled at 4 °C with the anti-HA 101R antibody; thereafter, HA-hIP expression was either analyzed directly (0 h internalization) or following incubation of cells with 1 ?
Spec (analyzed) Regulation (following) of Spec (analyzed) Gene_expression (expression) of hIP
5) Confidence 0.04 Published 2008 Journal Biochim Biophys Acta Section Body Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.17
These data confirm that both the wild type hIP and its truncated variants hIP?
Regulation (truncated) of Gene_expression (variants) of hIP
6) Confidence 0.04 Published 2008 Journal Biochim Biophys Acta Section Body Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.15
Herein the involvement of Rab5 in regulating cicaprost-induced internalization of the hIP expressed in human embryonic kidney 293 cells was investigated.
Regulation (regulating) of Gene_expression (expressed) of hIP in embryonic kidney
7) Confidence 0.02 Published 2008 Journal Biochim Biophys Acta Section Abstract Doc Link PMC2680976 Disease Relevance 0 Pain Relevance 0.13

General Comments

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