INT125549

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP2B6) endoplasmic reticulum (CYP2B6) cytoplasm (FGFR1)
cytosol (FGFR1) extracellular region (FGFR1) nucleus (FGFR1)
CYP2B6 (Homo sapiens)
FGFR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 4 78.84 Quite High
Paracetamol 1 66.32 Quite High
Disease Link Frequency Relevance Heat
Hepatotoxicity 1 72.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that SAM interacts with cytochrome P450s, especially CYP2E1, and inhibits the catalytic activity of CYP2E1 in a reversible and non competitive manner.
P450s Binding (interacts) of SAM
1) Confidence 0.00 Published 2005 Journal Biochem. Pharmacol. Section Abstract Doc Link 15763544 Disease Relevance 0.07 Pain Relevance 0.13

General Comments

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