INT125583

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (HSPG2) small molecule metabolic process (HSPG2) extracellular region (HSPG2)
plasma membrane (HSPG2) extracellular matrix organization (HSPG2) lipid metabolic process (HSPG2)
Anatomy Link Frequency
ventral 2
HSPG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Ventral tegmentum 4 99.68 Very High Very High Very High
addiction 2 98.64 Very High Very High Very High
Morphine 3 97.60 Very High Very High Very High
Eae 1 75.00 Quite High
Cannabinoid receptor 1 64.76 Quite High
antagonist 10 5.00 Very Low Very Low Very Low
Cannabinoid 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 98.64 Very High Very High Very High
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Cough 1 5.00 Very Low Very Low Very Low
Burns 1 5.00 Very Low Very Low Very Low
Pharyngitis 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Toothache 1 5.00 Very Low Very Low Very Low
Acute Monocytic Leukemia 1 5.00 Very Low Very Low Very Low
Snake Bites 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we mimicked the biological response of phospholipase C-gamma (PLC gamma) induction in the ventral tegmental area (VTA) observed after chronic morphine using viral-mediated gene transfer.
Regulation (response) of Positive_regulation (induction) of PLC in ventral associated with ventral tegmentum and morphine
1) Confidence 0.44 Published 2005 Journal Synapse Section Abstract Doc Link 15765533 Disease Relevance 0.10 Pain Relevance 0.51
Echinacea-induced [Ca2+]i increases in HEK293 cells appear to be associated with release of Ca2+ from IP3-sensitive intracellular stores, and this process may involve PLC activation
Spec (may) Regulation (involve) of Positive_regulation (activation) of PLC
2) Confidence 0.07 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3002894 Disease Relevance 0 Pain Relevance 0.03

General Comments

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