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Context Info
Confidence 0.16
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Col3a1) extracellular region (Col3a1)
Anatomy Link Frequency
bladders 1
Col3a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 5 100.00 Very High Very High Very High
agonist 10 99.32 Very High Very High Very High
cytokine 27 88.96 High High
intrathecal 1 88.24 High High
qutenza 1 86.28 High High
Spinal cord 1 72.36 Quite High
Central nervous system 1 68.08 Quite High
Inflammation 28 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 38 99.70 Very High Very High Very High
Injury 14 93.56 High High
Urinary Dysfunction 4 92.68 High High
Wound Healing 11 87.84 High High
Overactive Bladder 2 86.96 High High
Meningomyelocele 1 77.44 Quite High
Stress 3 69.36 Quite High
INFLAMMATION 31 5.00 Very Low Very Low Very Low
Anastomotic Leak 4 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphometric studies on animal or human bladder strips have demonstrated an increased expression of proteolytic enzymes and endogenous tissue inhibitors of metalloproteinases (MMP-1) and type III collagen mRNA in hypocompliant neurogenic bladders.
Negative_regulation (inhibitors) of type III collagen mRNA in bladders associated with metalloproteinase
1) Confidence 0.16 Published 2004 Journal Prog. Urol. Section Abstract Doc Link 15776894 Disease Relevance 0.46 Pain Relevance 0.25
were decreased; Type I collagen mRNA expression increased in hypoxic animals while Type III collagen was reduced with both GLP-2 agonists.
Negative_regulation (reduced) of Type III collagen associated with hypoxia and agonist
2) Confidence 0.05 Published 2010 Journal Gastroenterology Research and Practice Section Abstract Doc Link PMC2952794 Disease Relevance 0.91 Pain Relevance 0.17

General Comments

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