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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.92
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
tendon 1
bladders 1
Mmp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 71 100.00 Very High Very High Very High
intrathecal 1 88.24 High High
qutenza 1 86.28 High High
anesthesia 1 76.20 Quite High
isoflurane 1 75.76 Quite High
Spinal cord 1 72.36 Quite High
Central nervous system 1 65.84 Quite High
Osteoarthritis 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urinary Dysfunction 4 92.68 High High
Cadaver 2 89.04 High High
Overactive Bladder 2 86.96 High High
Tendinopathy 5 82.28 Quite High
Wound Healing 2 79.76 Quite High
Sprains And Strains 2 79.60 Quite High
Meningomyelocele 1 77.44 Quite High
Injury 5 60.28 Quite High
Rotator Cuff Tears 30 50.00 Quite Low
Arthropathy 7 40.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MCL gene expression of collagen type I, collagen type III, collagen type V, fibronectin, decorin, biglycan, lysyl oxidase, matrix metalloproteinase-2, and tissue inhibitor of matrix metalloproteinase-1, measured by real-time quantitative PCR, demonstrated differential expression in the HLU-healing groups compared with Amb-healing groups at both the 3- and 7-wk time points.
Negative_regulation (inhibitor) of matrix metalloproteinase-1 in MCL associated with metalloproteinase
1) Confidence 0.42 Published 2007 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 17699562 Disease Relevance 0.22 Pain Relevance 0.21
In their rabbit flexor tendon model, Asundi and Rempel described MMP 3, but not MMP 1 inhibition [25].
Negative_regulation (inhibition) of MMP 1 in tendon associated with metalloproteinase
2) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2998463 Disease Relevance 0.25 Pain Relevance 0.57
Morphometric studies on animal or human bladder strips have demonstrated an increased expression of proteolytic enzymes and endogenous tissue inhibitors of metalloproteinases (MMP-1) and type III collagen mRNA in hypocompliant neurogenic bladders.
Negative_regulation (inhibitors) of MMP-1 in bladders associated with metalloproteinase
3) Confidence 0.20 Published 2004 Journal Prog. Urol. Section Abstract Doc Link 15776894 Disease Relevance 0.46 Pain Relevance 0.25

General Comments

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