INT125766

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 2005
Last Reported 2010
Negated 0
Speculated 3
Reported most in Body
Documents 7
Total Number 10
Disease Relevance 4.31
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (S100b) nucleus (S100b) cytoplasm (S100b)
Anatomy Link Frequency
neuronal 1
CSF 1
brain 1
astrocytes 1
neural 1
S100b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Gabapentin 2 100.00 Very High Very High Very High
anesthesia 6 99.98 Very High Very High Very High
Nicotine 1 97.52 Very High Very High Very High
Inflammation 20 93.28 High High
opiate 5 91.20 High High
Central nervous system 4 90.00 High High
Morphine 2 88.04 High High
Glutamate receptor 1 85.12 High High
Hippocampus 19 80.16 Quite High
Pyramidal cell 24 78.24 Quite High
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 15 99.84 Very High Very High Very High
Hypothermia 4 99.52 Very High Very High Very High
Diabetes Mellitus 2 98.92 Very High Very High Very High
Myocardial Infarction 30 98.72 Very High Very High Very High
Arrhythmias 2 Under Development 2 96.12 Very High Very High Very High
Systemic Lupus Erythematosus 2 95.68 Very High Very High Very High
Shock 2 95.52 Very High Very High Very High
Brain Ischemia 4 94.28 High High
Injury 7 93.44 High High
Hypoxia 11 93.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIM: To investigate the effect of gabapentin on neural [neuron-specific enolase (NSE)] and glial markers [glial fibrillary acidic protein (GFAP) and S100B] in different brain regions of diabetic rats.
Spec (investigate) Regulation (effect) of S100B in neural associated with diabetes mellitus and gabapentin
1) Confidence 0.38 Published 2005 Journal Acta Pharmacol. Sin. Section Abstract Doc Link 15780189 Disease Relevance 0.17 Pain Relevance 0.21
OBJECTIVE: To analyze the diagnostic and prognostic values of urinary S100B level and lactate/creatinine ratio in newborns with HIE.
Spec (analyze) Regulation (values) of S100B
2) Confidence 0.19 Published 2010 Journal Neonatology Section Body Doc Link 19590245 Disease Relevance 0.19 Pain Relevance 0
A cutoff value for the S100B level of 0.47 microg/l on day 3 after birth had a sensitivity of 90% and specificity of 92% for prediction of HIE.
Regulation (value) of S100B
3) Confidence 0.19 Published 2010 Journal Neonatology Section Body Doc Link 19590245 Disease Relevance 0.13 Pain Relevance 0
A nonspecific elevating effect on aAbs to the brain structural protein S100B was observed for all drugs tested versus controls.
Regulation (effect) of protein S100B in brain
4) Confidence 0.11 Published 2006 Journal Neurosci. Lett. Section Abstract Doc Link 16687214 Disease Relevance 0.07 Pain Relevance 0.74
OBJECTIVE: To observe the effect of hydroxyethyl starch (HES) 130/0.4 on S100B protein level and cerebral metabolism of oxygen in open cardiac surgery under cardiopulmonary bypass (CPB) and to explore whether it has the protective effect of 6%HES130/0.4 as priming solution on cerebral injury during CPB and explore the probable mechanism.
Regulation (effect) of S100B associated with brain injury
5) Confidence 0.10 Published 2007 Journal Zhonghua Yi Xue Za Zhi Section Abstract Doc Link 17923015 Disease Relevance 0.09 Pain Relevance 0
The up-regulation of the S100B protein has been found in previous studies [37], [38] suggesting an activation of pathways, which lead to increased intracellular Ca2+ concentrations in astrocytes [36].
Regulation (regulation) of S100B protein in astrocytes
6) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2873964 Disease Relevance 0.83 Pain Relevance 0.09
The aim of this study is to determine S100B protein levels in serum and cerebrospinal fluid (CSF) in patients with different forms of neruopsychiatric systemic lupus erythematosus (NPSLE).
Spec (determine) Regulation (determine) of S100B in CSF associated with systemic lupus erythematosus
7) Confidence 0.05 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 17955279 Disease Relevance 0.34 Pain Relevance 0
[Effect of hydroxyethyl starch 130/0.4 on S100B protein level and cerebral oxygen metabolism in open cardiac surgery under cardiopulmonary bypass].
Regulation (Effect) of S100B associated with anesthesia
8) Confidence 0.04 Published 2007 Journal Zhonghua Yi Xue Za Zhi Section Title Doc Link 17923015 Disease Relevance 0 Pain Relevance 0.10
S-100B and neuronal-specific enolase might, therefore, be potential markers of cerebral damage and BBB alterations in ARDS patients [28].
Regulation (alterations) of S-100B in neuronal associated with adult respiratory distress syndrome
9) Confidence 0.02 Published 2007 Journal Crit Care Section Body Doc Link PMC2206421 Disease Relevance 1.52 Pain Relevance 0.19
A recent study suggests that the use of therapeutic hypothermia reduces the prognostic value of NSE and S100 B to predict poor outcomes after cardiac arrest [29], which does not seem to happen with the use of evoked potentials [33].
Regulation (value) of S100 B associated with hypothermia and myocardial infarction
10) Confidence 0.01 Published 2006 Journal Crit Care Section Body Doc Link PMC1751053 Disease Relevance 0.98 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox