INT125770

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Context Info
Confidence 0.29
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GLP1R, GCG) plasma membrane (GLP1R, GCG) cell proliferation (GCG)
signal transduction (GCG) extracellular space (GCG) extracellular region (GCG)
Anatomy Link Frequency
alpha cells 2
GLP1R (Homo sapiens)
GCG (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 25 97.28 Very High Very High Very High
Central nervous system 1 88.24 High High
Paracetamol 1 63.20 Quite High
headache 2 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 49 75.00 Quite High
Hypoglycemia 10 64.88 Quite High
Disease Progression 5 38.32 Quite Low
Weight Loss 8 5.00 Very Low Very Low Very Low
Vomiting 8 5.00 Very Low Very Low Very Low
Body Weight 7 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 5 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Renal Insufficiency 4 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was hypothesized that a major component of the glycaemic effect is attributable to the known action of GLP-1 to inhibit gastric emptying and to inhibit glucagon secretion.
GLP-1 Negative_regulation (inhibit) of Localization (secretion) of glucagon
1) Confidence 0.29 Published 2005 Journal Regul. Pept. Section Abstract Doc Link 15780434 Disease Relevance 0.33 Pain Relevance 0.11
GLP-1 stimulates insulin secretion of the beta cells and additionally inhibits glucagon secretion from the alpha cells.
GLP-1 Negative_regulation (inhibits) of Localization (secretion) of glucagon in alpha cells
2) Confidence 0.11 Published 2010 Journal Pediatr Nephrol Section Body Doc Link PMC2874027 Disease Relevance 0.32 Pain Relevance 0.04

General Comments

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