INT125780

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgb3) plasma membrane (Itgb3)
Anatomy Link Frequency
platelet 1
Itgb3 (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 1 99.72 Very High Very High Very High
cINOD 2 84.72 Quite High
agonist 1 76.80 Quite High
cva 1 29.68 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 1 96.68 Very High Very High Very High
Myocardial Infarction 1 96.24 Very High Very High Very High
INFLAMMATION 2 84.32 Quite High
Cardiovascular Disease 1 84.28 Quite High
Thrombosis 1 79.88 Quite High
Atherosclerosis 1 79.00 Quite High
Acute Myeloid Leukemia 4 62.24 Quite High
Myeloid Leukemia 1 48.48 Quite Low
Anaemia 1 30.84 Quite Low
Hemorrhage 1 29.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that a blockade of Meis1 expression with Meis1 siRNA was associated with a decrease in Itgb3 mRNA.
Negative_regulation (decrease) of Itgb3
1) Confidence 0.39 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0.06 Pain Relevance 0
Sustained inhibition of platelet TxA(2) by aspirin affords cardiovascular benefit, despite concomitant inhibition of PGI(2).
Negative_regulation (inhibition) of platelet TxA in platelet associated with aspirin
2) Confidence 0.06 Published 2005 Journal Curr Opin Pharmacol Section Abstract Doc Link 15780832 Disease Relevance 0.60 Pain Relevance 0.25

General Comments

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