INT1258

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Context Info
Confidence 0.54
First Reported 1976
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.12
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tshr) signal transducer activity (Tshr)
Anatomy Link Frequency
thyroid 1
Tshr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
withdrawal 8 96.56 Very High Very High Very High
imagery 1 90.84 High High
anesthesia 2 90.24 High High
headache 4 86.32 High High
cva 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Graves' Ophthalmopathy 1 99.96 Very High Very High Very High
Disease 1 99.64 Very High Very High Very High
Postmortem Changes 2 98.76 Very High Very High Very High
Thyroid Disease 4 89.84 High High
Ocular Toxicity (including Many Sub-types) 1 88.92 High High
Headache 2 86.32 High High
Papilledema 2 86.32 High High
Pseudotumor Cerebri 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two weeks after PTU treatment, circulating thyrotropin was increased to a maximum of 19-fold and a further enhancement ("rebound") was observed after PTU withdrawal.
Positive_regulation (increased) of thyrotropin associated with withdrawal
1) Confidence 0.54 Published 1976 Journal Endocrinol. Jpn. Section Abstract Doc Link 182477 Disease Relevance 0.07 Pain Relevance 0.26
Changes in cyclic AMP level of rat thyroid by acute and chronic stimulation of thyrotropin in vivo.
Positive_regulation (stimulation) of thyrotropin in thyroid
2) Confidence 0.36 Published 1976 Journal Endocrinol. Jpn. Section Title Doc Link 182477 Disease Relevance 0.10 Pain Relevance 0.23
As TSH receptor stimulating antibodies (TSHR-Ab) were elevated Graves' disease was diagnosed.
Positive_regulation (elevated) of TSHR-Ab associated with graves' ophthalmopathy and disease
3) Confidence 0.16 Published 2008 Journal J. Pediatr. Endocrinol. Metab. Section Abstract Doc Link 19189707 Disease Relevance 0.95 Pain Relevance 0.25

General Comments

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