INT125832

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.33
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TTPA) transport (TTPA) intracellular (TTPA)
lipid metabolic process (TTPA) cytoplasm (TTPA)
TTPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 77.64 Quite High
cytokine 1 47.12 Quite Low
agonist 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 3 99.00 Very High Very High Very High
Myelodysplastic Syndromes 6 98.80 Very High Very High Very High
Metastasis 18 91.44 High High
Arthralgia 1 77.64 Quite High
Conjunctivitis 1 77.16 Quite High
Cheilitis 1 76.52 Quite High
Spontaneous Abortion 2 64.88 Quite High
Disease Progression 8 60.12 Quite High
Advanced Or Metastatic Breast Cancer 20 50.00 Quite Low
Toxicity 6 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Median TTP values for letrozole and tamoxifen in the different subgroups are shown in TableĀ 1.
Regulation (values) of TTP
1) Confidence 0.05 Published 2007 Journal Breast Cancer Res Treat Section Body Doc Link PMC2001219 Disease Relevance 0.48 Pain Relevance 0
The majority of these results show no effect on TTP, delayed conception, or infertility of maternal [75,76] or paternal [77,78] exposure, although one study did suggest reduced fecundability among women with high consumption of fatty fish from the Great Lakes [78].
Neg (no) Regulation (effect) of TTP associated with reprotox - general 3
2) Confidence 0.02 Published 2008 Journal Environ Health Section Body Doc Link PMC2438351 Disease Relevance 0.23 Pain Relevance 0
Based on these results, the combination of ATRA and tocopherol-alpha is not recommended for the treatment of del(5q) MDS.
Neg (not) Regulation (recommended) of tocopherol-alpha associated with myelodysplastic syndromes
3) Confidence 0.02 Published 2005 Journal Ann. Hematol. Section Abstract Doc Link 15785949 Disease Relevance 0.62 Pain Relevance 0.08

General Comments

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