INT125856

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) kinase activity (Insrr)
signal transducer activity (Oprm1)
Oprm1 (Mus musculus)
Insrr (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 9 100.00 Very High Very High Very High
opioid receptor 6 100.00 Very High Very High Very High
Analgesic 2 100.00 Very High Very High Very High
Morphine 4 98.72 Very High Very High Very High
Opioid 2 97.92 Very High Very High Very High
Pain 1 94.92 High High
addiction 1 91.52 High High
antagonist 2 81.32 Quite High
Antinociceptive 1 80.08 Quite High
agonist 2 78.00 Quite High
Disease Link Frequency Relevance Heat
Pain 1 94.92 High High
Targeted Disruption 1 88.56 High High
Drug Dependence 1 74.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo activation of a mutant mu-opioid receptor by naltrexone produces a potent analgesic effect but no tolerance: role of mu-receptor activation and delta-receptor blockade in morphine tolerance.
Positive_regulation (activation) of mu-opioid receptor Regulation (role) of Positive_regulation (activation) of receptor associated with analgesic, tolerance, opioid receptor and morphine
1) Confidence 0.01 Published 2005 Journal J. Neurosci. Section Title Doc Link 15788780 Disease Relevance 0.26 Pain Relevance 1.43

General Comments

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