INT125891

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Context Info
Confidence 0.78
First Reported 2005
Last Reported 2005
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 3.65
Pain Relevance 2.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Mapkapk2) response to stress (Mapkapk2) cytoplasm (Mapkapk2)
Anatomy Link Frequency
TMJ 3
Mapkapk2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Snapping jaw 35 99.52 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 10 100.00 Very High Very High Very High
Temporomandibular Joint Syndrome 35 99.52 Very High Very High Very High
Shock 5 94.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, confocal microscopy with double staining was employed to demonstrate the colocalization of MAPKAPK-2 and Hsp25.
Localization (colocalization) of MAPKAPK-2
1) Confidence 0.78 Published 2005 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 15791578 Disease Relevance 0.74 Pain Relevance 0.48
Double immunostaining under a confocal microscope succeeded in demonstrating the colocalization of MAPKAPK-2 and Hsp25 immunoreactions in the cytoplasm of fibroblastic type B synoviocytes in the TMJ.
Localization (colocalization) of MAPKAPK-2 in TMJ associated with snapping jaw
2) Confidence 0.78 Published 2005 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 15791578 Disease Relevance 0.71 Pain Relevance 0.49
The present study was undertaken to examine the localization of MAPKAPK-2 in the rat TMJ by immunocytochemical techniques.
Spec (examine) Localization (localization) of MAPKAPK-2 in TMJ associated with snapping jaw
3) Confidence 0.78 Published 2005 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 15791578 Disease Relevance 0.75 Pain Relevance 0.48
Immunocytochemical localization of MAPKAPK-2 and Hsp25 in the rat temporomandibular joint.
Localization (localization) of MAPKAPK-2 in temporomandibular joint associated with snapping jaw
4) Confidence 0.78 Published 2005 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Title Doc Link 15791578 Disease Relevance 0.74 Pain Relevance 0.48
This protein is the major substrate of mitogen-activated protein kinase-activated protein kinase-2 (MAPKAPK-2), which mediates an intracellular stress-activated signaling pathway to stimulate cytosolic actin reorganization under various stresses.
Localization (reorganization) of MAPKAPK-2 associated with stress
5) Confidence 0.73 Published 2005 Journal The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology Section Abstract Doc Link 15791578 Disease Relevance 0.71 Pain Relevance 0.42

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