INT125950

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 1.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Syt17, Trpv1) cytosol (Trpv1) plasma membrane (Trpv1)
molecular_function (Syt17) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
nociceptor 1
Syt17 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 10 100.00 Very High Very High Very High
nociceptor 7 99.40 Very High Very High Very High
Hyperalgesia 1 99.18 Very High Very High Very High
qutenza 2 90.84 High High
Pain 1 75.00 Quite High
Inflammation 1 64.36 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 1 99.18 Very High Very High Very High
Nociception 1 97.70 Very High Very High Very High
Targeted Disruption 1 96.60 Very High Very High Very High
Pain 1 75.00 Quite High
INFLAMMATION 1 64.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, TRPV1 knockout mice showed almost no change in BK-induced nociceptive behavior and nociceptor excitation, although BK-induced heat hyperalgesia completely disappeared, suggesting that TRPV1 was not the sole channel that was modulated by BK to depolarize nociceptor terminals.
BK Regulation (modulated) of TRPV1 in nociceptor associated with nociception, targeted disruption, hyperalgesia, nociceptor and bradykinin
1) Confidence 0.11 Published 2005 Journal Nihon Shinkei Seishin Yakurigaku Zasshi Section Abstract Doc Link 15796068 Disease Relevance 0.43 Pain Relevance 1.28

General Comments

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