INT126030

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.92
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CFD) extracellular space (CFD) extracellular region (CFD)
CFD (Homo sapiens)
Pain Link Frequency Relevance Heat
pain pelvic 7 100.00 Very High Very High Very High
fibrosis 110 99.88 Very High Very High Very High
backache 1 75.00 Quite High
alcohol 2 70.16 Quite High
antagonist 4 69.68 Quite High
Inflammation 64 5.00 Very Low Very Low Very Low
cytokine 14 5.00 Very Low Very Low Very Low
midbrain 10 5.00 Very Low Very Low Very Low
Multiple sclerosis 10 5.00 Very Low Very Low Very Low
metalloproteinase 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 7 100.00 Very High Very High Very High
Fibrosis 100 99.88 Very High Very High Very High
Apoptosis 15 99.84 Very High Very High Very High
Infection 40 99.22 Very High Very High Very High
Disease 47 99.08 Very High Very High Very High
Dengue 104 99.02 Very High Very High Very High
Stress Incontinence 5 96.68 Very High Very High Very High
Sunburn 2 95.84 Very High Very High Very High
Vomiting 2 95.12 Very High Very High Very High
Flavivirus Infection 80 94.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies on the pharmacokinetics and metabolism of PFD conducted by Shi et al [2] evaluated the pharmacokinetics of single and multiple oral doses of PFD in healthy adults in a randomized, dose-escalating study.
Regulation (metabolism) of PFD
1) Confidence 0.21 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2944211 Disease Relevance 0.40 Pain Relevance 0.04
Because apoptosis could partly explain the loss of cells associated with fibrosis, the influence of PFD on apoptosis-regulatory genes to cause a reduction in apoptosis may explain some of its antifibrotic properties [66].


Regulation (influence) of PFD associated with fibrosis and apoptosis
2) Confidence 0.12 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2944211 Disease Relevance 0.88 Pain Relevance 0.12
The occurrence of PFD and PLBP was influenced by a confounding effect of age.
Regulation (influenced) of PFD associated with pain pelvic
3) Confidence 0.12 Published 2005 Journal Int Urogynecol J Pelvic Floor Dysfunct Section Abstract Doc Link 15803285 Disease Relevance 0.99 Pain Relevance 0.68
These data suggest that during acute dengue infection, the patients who are more capable of modulating their levels of factor D will exhibit the mild disease phenotype DF.
Regulation (modulating) of factor D associated with dengue, disease and infection
4) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2728508 Disease Relevance 1.64 Pain Relevance 0
For EVR DF and duration, we first removed the effect of individual by performing a univariate ANOVA (independent variable?
Regulation (effect) of EVR DF
5) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2671607 Disease Relevance 0 Pain Relevance 0

General Comments

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