INT12616
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The resultant mimicry of REM cellular events by carbachol extends to membrane potential depolarization, increased cellular excitability, enhancement of PSPs from reticular stimulation, and the absence of a burst discharge pattern. | |||||||||||||||
| |||||||||||||||
|
During hospital stay, PSP/reg levels were elevated significantly in patients with sepsis (146.4 ng/mL) and in patients with infections (111.4 ng/mL) compared with patients without infections (22.8 ng/mL). | |||||||||||||||
| |||||||||||||||
|
However, after stress (e.g., anesthesia), PSP/reg levels are increased transiently in animals without pancreatic injury. | |||||||||||||||
| |||||||||||||||
|
In three neurons a progressive increase in the size and duration of the C-fiber PSPs occurred, resulting in an increase in the number of action potentials (windup), whereas in two, the repeated stimulation resulted in a progressive moderate depolarization of the neurons and an increase in the total number of action potentials evoked at both early and late latencies. | |||||||||||||||
| |||||||||||||||
|
The gene expression observations are consistent with the results of previous studies: first, the documented changes in Reg1? | |||||||||||||||
| |||||||||||||||
|
results in a compensatory increase in Reg1? | |||||||||||||||
| |||||||||||||||
|
After 6 months the posterior tibial pressure (PTP) at the end of the treadmill exercise test also increased from 40 +/- 19 to 63 +/- 12 (p < 0.05). | |||||||||||||||
| |||||||||||||||
|
Furthermore, the serum PSP/reg-protein concentration was also significantly increased in liver cirrhosis, choledocholithiasis, and various cancers of the digestive system, and was extremely high in all patients tested with chronic renal failure. | |||||||||||||||
| |||||||||||||||
|
NSAIDs were recently reported to cause mitochondrial injury: to dissipate the mitochondrial transmembrane potential (MTP), and to induce mitochondrial permeability transition pore (PTP), which liberates cytochrome c. | |||||||||||||||
| |||||||||||||||
|
Whereas only 7 of these patients showed a normal serum PSP/reg-protein concentration and a significantly increased elastase-I concentration, 15 of these patients showed a significantly increased serum PSP/reg-protein concentration and a normal serum elastase-I concentration. | |||||||||||||||
| |||||||||||||||
|
This implied that for a given excitatory synaptic conductance the distal dendrites generated larger PSPs than proximal dendrites. | |||||||||||||||
| |||||||||||||||
|
Activated pancreatic enzyme and pancreatic stone protein (PSP/reg) in bile of patients with pancreaticobiliary maljunction/ choledochal cysts. | |||||||||||||||
| |||||||||||||||
|
This maximum amplitude was similar to the one reached if the PSPs were activated during the up states. | |||||||||||||||
| |||||||||||||||
|
In the case that induced PSPs were followed by an up state, its initiation was generally not as steep as in barrel cortex and therefore the PSPs' peak occurred earlier than the local circuit recruitment. | |||||||||||||||
| |||||||||||||||
|
The amplitude of PSPs evoked during the 200 ms following the occurrence of the up state was still increased to an average of the normalized values of ×1.9 times (2.3±0.7 mV) the amplitude of the PSPs occurring during downstates (Fig. 4D,E,F). | |||||||||||||||
| |||||||||||||||
|
We observed that intracortical PSPs evoked during the 200 ms following the occurrence of the up states (End period, see Results) were still greatly increased in amplitude in vivo to about 1.2 times the amplitude of the PSPs occurring during downstates (Fig. 4). | |||||||||||||||
| |||||||||||||||
|
The disparity between studies could be due to different reasons: 1) different amplitude of sensory evoked potentials (see Fig. 8C); 2) stimulating one whisker versus several whiskers, 3) averaging PSPs that trigger an up state together with those occurring during down states and comparing them with PSPs in up states, 4) different cortical areas, species, or specific synaptic connections that behave differently [40], [41]. | |||||||||||||||
| |||||||||||||||
|
To explore which mechanisms could contribute to the increase in amplitude of PSPs during up states we first considered the effect of membrane voltage depolarization typical of up states. | |||||||||||||||
| |||||||||||||||
|
Preincubation of human trophoblastic cells with 0.1 microgram/ml Islet-Activating-Protein (IAP; also called pertussis toxin) did not modify basal adenylate cyclase activity but abolished the inhibition of adenylate cyclase activity by EKC, indicating that the effect of opiates on cAMP production was mediated by an IAP-sensitive GTP binding protein. | |||||||||||||||
| |||||||||||||||
|
In hippocampal slices, the PSPs that are enhanced are monosynaptic [57]. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.