INT126199

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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.45
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (S100a4)
S100a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
agonist 4 99.44 Very High Very High Very High
COX2 6 98.60 Very High Very High Very High
Hippocampus 4 96.96 Very High Very High Very High
cINOD 10 96.64 Very High Very High Very High
Inflammatory response 4 93.04 High High
Inflammatory marker 2 87.12 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 14 100.00 Very High Very High Very High
Targeted Disruption 2 99.20 Very High Very High Very High
Amyloid Plaque 6 98.52 Very High Very High Very High
Disease 6 96.72 Very High Very High Very High
Alzheimer's Dementia 2 67.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
Negative_regulation (reduces) of Abeta1-42 associated with targeted disruption, inflammation, agonist and cox2
1) Confidence 0.08 Published 2005 Journal Brain Section Title Doc Link 15817521 Disease Relevance 0.99 Pain Relevance 0.69
Additionally, animals treated with pioglitazone revealed a 27% reduction in the levels of soluble Abeta1-42 peptide.
Negative_regulation (reduction) of Abeta1-42
2) Confidence 0.08 Published 2005 Journal Brain Section Abstract Doc Link 15817521 Disease Relevance 0.46 Pain Relevance 0.69

General Comments

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