INT12628

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Context Info
Confidence 0.30
First Reported 1986
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 2.45
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cish)
Cish (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 104 100.00 Very High Very High Very High
Analgesic 1 99.92 Very High Very High Very High
Opioid 2 98.80 Very High Very High Very High
palliative 1 93.52 High High
Morphine 1 43.40 Quite Low
narcan 1 42.64 Quite Low
antinociception 1 32.24 Quite Low
Potency 1 25.40 Quite Low
Pain 1 25.00 Low Low
Dysuria 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Sepsis 74 100.00 Very High Very High Very High
Cleidocranial Dysplasia 8 100.00 Very High Very High Very High
Carcinoma In Situ 8 100.00 Very High Very High Very High
Genital Human Papilloma Virus 1 99.98 Very High Very High Very High
Recurrence 5 98.00 Very High Very High Very High
Bladder Cancer 2 95.76 Very High Very High Very High
Carcinoma 1 87.28 High High
Transitional Cell Carcinoma 1 87.20 High High
Infection 4 84.04 Quite High
Critical Illness 18 80.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Five histopathological patterns were recognized: normal urothelium, mild, moderate and severe dysplasia, and carcinoma in situ (CIS).
CIS Binding (recognized) of associated with carcinoma in situ and cleidocranial dysplasia
1) Confidence 0.30 Published 1986 Journal Aust N Z J Surg Section Abstract Doc Link 3459428 Disease Relevance 1.10 Pain Relevance 0
Condylomata acuminata associated with CIS in 16 of 17 patients recurred rapidly in 7 patients after PDT.
CIS Binding (associated) of associated with genital human papilloma virus and carcinoma in situ
2) Confidence 0.30 Published 1993 Journal J Gynecol Surg Section Abstract Doc Link 10148524 Disease Relevance 0.56 Pain Relevance 0.09
(+)-cis-3-methylfentanyl and its analogs bind pseudoirreversibly to the mu opioid binding site: evidence for pseudoallosteric modulation.
cis-3-methylfentanyl Binding (bind) of associated with analgesic and opioid
3) Confidence 0.21 Published 1991 Journal Neuropharmacology Section Title Doc Link 1650928 Disease Relevance 0 Pain Relevance 0.20
Increased hepatic mRNA of SOCS proteins has been shown to occur transiently in abdominal sepsis and to be temporally associated with the development of GH resistance [13].
SOCS Binding (associated) of associated with sepsis
4) Confidence 0.16 Published 2007 Journal Crit Care Section Body Doc Link PMC2206515 Disease Relevance 0.46 Pain Relevance 0.27
We studied the effect of nutrition and the route of delivery of nutrition on cytokine profiles, the growth hormoneĀ–insulin-like growth factor-1 (IGF-I) axis and a potential mechanism for immune and anabolic system interaction, the suppressors of cytokine signaling (SOCS), in rodents with and without sepsis.


SOCS Binding (interaction) of associated with sepsis and cytokine
5) Confidence 0.14 Published 2007 Journal Crit Care Section Abstract Doc Link PMC2206515 Disease Relevance 0.33 Pain Relevance 0.21

General Comments

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