INT126323

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2005
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 6
Total Number 8
Disease Relevance 3.17
Pain Relevance 2.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (TGFBI) extracellular space (TGFBI) extracellular region (TGFBI)
plasma membrane (TGFBI) extracellular matrix organization (TGFBI)
Anatomy Link Frequency
posterior 2
cortex 2
TGFBI (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 29 100.00 Very High Very High Very High
Opioid 3 99.60 Very High Very High Very High
Migraine 7 98.32 Very High Very High Very High
narcan 9 97.28 Very High Very High Very High
antagonist 7 97.10 Very High Very High Very High
long-term potentiation 5 96.92 Very High Very High Very High
Pain 9 96.80 Very High Very High Very High
Hippocampus 6 95.12 Very High Very High Very High
agonist 4 94.00 High High
ischemia 1 91.76 High High
Disease Link Frequency Relevance Heat
Depression 29 100.00 Very High Very High Very High
Headache 6 98.32 Very High Very High Very High
Anaerobic Bacterial Infections 1 97.56 Very High Very High Very High
Corneal Opacity 2 96.96 Very High Very High Very High
Pain 5 96.80 Very High Very High Very High
Epilepsy 2 96.00 Very High Very High Very High
Amyloidosis 6 95.28 Very High Very High Very High
Adhesions 10 93.84 High High
Brain Hemorrhage 1 91.76 High High
Injury 5 61.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TGFBI is also a major gene responsible for most LCD cases.
Regulation (responsible) of TGFBI
1) Confidence 0.59 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2822555 Disease Relevance 0.09 Pain Relevance 0
Biologic samples (peripheral blood, buccal swab, saliva) were collected from six members of the pedigree affected with CDB, one member affected with posterior polymorphous dystrophy (PPCD), three unaffected members, and five individuals of unknown affected status due to their age.
Regulation (affected) of CDB in posterior
2) Confidence 0.38 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2518171 Disease Relevance 0 Pain Relevance 0
One hundred healthy volunteers (Han ethnicity) were recruited as controls for sequence analysis of TGFBI.
Regulation (controls) of TGFBI
3) Confidence 0.38 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2822555 Disease Relevance 0.25 Pain Relevance 0
Biologic samples (peripheral blood, buccal swab, saliva) were collected from six members of the pedigree affected with CDB, one member affected with posterior polymorphous dystrophy (PPCD), three unaffected members, and five individuals of unknown affected status due to their age.
Regulation (affected) of CDB in posterior
4) Confidence 0.28 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2518171 Disease Relevance 0 Pain Relevance 0
To study whether these compounds act by influencing CSD, we applied different drugs topically to an area of the exposed cortex of anesthetized adult rats and observed the migration of CSD-related DC potential deflections across the treated area.
Spec (whether) Regulation (influencing) of CSD in cortex associated with depression
5) Confidence 0.23 Published 2005 Journal J. Cereb. Blood Flow Metab. Section Abstract Doc Link 15829916 Disease Relevance 1.10 Pain Relevance 1.03
Despite the importance of the CSD, precise analyses of spontaneous healing capacity have not been discussed in the literature, and different studies have considered CSDs in the range of 10-15 mm to be suitable [9,10,16-18].
Regulation (importance) of CSD
6) Confidence 0.19 Published 2010 Journal Journal of Periodontal & Implant Science Section Body Doc Link PMC2931306 Disease Relevance 0 Pain Relevance 0
In vitro and ex vivo/in vitro brain slice techniques were used to investigate CSD effects on the field excitatory postsynaptic potentials (fEPSP) and tetanus-induced long-term potentiation (LTP) in combined rat hippocampus-cortex slices.
Spec (investigate) Regulation (effects) of CSD in cortex associated with depression, anaerobic bacterial infections, hippocampus and long-term potentiation
7) Confidence 0.18 Published 2006 Journal Eur. J. Neurosci. Section Abstract Doc Link 16553774 Disease Relevance 1.02 Pain Relevance 0.90
Our results demonstrate, for the first time, that chronic neonatal exposure of rats to the opioid antagonist naloxone results in an impairing propagation of the CSD that is long lasting, suggesting the existence of one or more opioid-mediated processes influencing CSD.
Regulation (influencing) of CSD associated with depression, antagonist, narcan and opioid
8) Confidence 0.18 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18601977 Disease Relevance 0.71 Pain Relevance 0.97

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox