INT126375

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Context Info
Confidence 0.58
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Gli3) intracellular (Gli3) cilium (Gli3)
DNA binding (Gli3) cytoplasm (Gli3) cytosol (Gli3)
Gli3 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 75.16 Quite High
Disease Link Frequency Relevance Heat
Synovial Chondromatosis 8 97.36 Very High Very High Very High
Cancer 1 81.24 Quite High
Arthropathy 1 75.92 Quite High
Pain 1 75.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine if hedgehog-mediated transcription predisposes to synovial chondromatosis, the extra-toes mutant mouse, which harbours a heterozygous mutation in the hedgehog transcriptional repressor, Gli3, resulting in decreased expression of Gli3 protein, was studied.
Negative_regulation (decreased) of Gene_expression (expression) of Gli3 associated with synovial chondromatosis
1) Confidence 0.58 Published 2005 Journal J. Pathol. Section Abstract Doc Link 15834844 Disease Relevance 0.79 Pain Relevance 0.08

General Comments

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