INT126578

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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Agtr2) plasma membrane (Agtr2) transcription factor binding (Agtr2)
signal transducer activity (Agtr2)
Anatomy Link Frequency
stroma 2
Agtr2 (Mus musculus)
Pain Link Frequency Relevance Heat
bradykinin 1 99.40 Very High Very High Very High
Neuropeptide 2 97.52 Very High Very High Very High
Enkephalin 1 96.64 Very High Very High Very High
substance P 1 96.16 Very High Very High Very High
Dynorphin 1 95.64 Very High Very High Very High
dopamine receptor 1 52.16 Quite High
agonist 1 50.72 Quite High
antagonist 7 48.72 Quite Low
Dopamine 1 48.40 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 11 98.16 Very High Very High Very High
Cancer 84 97.60 Very High Very High Very High
Pancreatic Cancer 21 96.56 Very High Very High Very High
Schizophrenia 2 84.48 Quite High
Apoptosis 15 69.44 Quite High
Targeted Disruption 3 62.72 Quite High
Death 3 5.00 Very Low Very Low Very Low
Pancreatic Ductal Carcinoma 3 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, in this study we sought to evaluate the role of AT2 receptor expression in stroma in the growth of pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer.
Regulation (role) of Gene_expression (expression) of AT2 receptor in stroma associated with adenocarcinoma and pancreatic cancer
1) Confidence 0.49 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2846883 Disease Relevance 0.87 Pain Relevance 0
Angiotensin-converting enzyme (ACE) is crucial in the synthesis of angiotensin II, breakdown of bradykinin and the hydrolysis of several other neuropeptides such as enkephalin, substance P, dynorphin and neurotensin.
Regulation (crucial) of Gene_expression (synthesis) of angiotensin II associated with dynorphin, neuropeptide, enkephalin, bradykinin and substance p
2) Confidence 0.05 Published 2005 Journal Neurosci. Lett. Section Abstract Doc Link 15854741 Disease Relevance 0.21 Pain Relevance 0.34

General Comments

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