INT126636

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.18
Pain Relevance 2.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Bdkrb2) plasma membrane (Bdkrb2) signal transducer activity (Bdkrb2)
Anatomy Link Frequency
neurons 1
dorsal root ganglia 1
Bdkrb2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 55 100.00 Very High Very High Very High
b2 receptor 13 100.00 Very High Very High Very High
dorsal root ganglion 113 96.32 Very High Very High Very High
cINOD 3 94.80 High High
Pain 17 91.32 High High
Inflammation 40 88.92 High High
diclofenac 1 82.40 Quite High
IPN 5 77.52 Quite High
Arthritis 28 77.12 Quite High
qutenza 2 76.56 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 113 96.32 Very High Very High Very High
Pain 14 91.32 High High
INFLAMMATION 38 88.92 High High
Inflammatory Pain 5 77.52 Quite High
Arthritis 30 77.12 Quite High
Hyperalgesia 7 67.60 Quite High
Arthralgia 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The functional interaction between B2R and TRPA1, as well as the modulation mechanism, was also observed in rat dorsal root ganglia neurons.
B2R Binding (interaction) of in dorsal root ganglia
1) Confidence 0.33 Published 2008 Journal Brain Section Abstract Doc Link 18356188 Disease Relevance 0.55 Pain Relevance 0.78
Currently it appears unlikely that zaltoprofen binds to specific sites on the protein of the bradykinin B2 receptor, hence we have examined the effect of zaltoprofen on bradykinin-induced responses of adult DRG neurons to investigate possible interaction sites.
bradykinin B2 receptor Binding (binds) of in neurons associated with dorsal root ganglion, b2 receptor and bradykinin
2) Confidence 0.31 Published 2005 Journal Neuropharmacology Section Abstract Doc Link 15857630 Disease Relevance 0.64 Pain Relevance 1.23
Bradykinin 2 receptor-like labelling
Bradykinin 2 receptor-like Binding (labelling) of associated with bradykinin
3) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860064 Disease Relevance 0.99 Pain Relevance 0.77

General Comments

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