INT126654

Context Info Confidence 0.03 First Reported 2005 Last Reported 2005 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.13 Pain Relevance 0.52

signal transducer activity (Oprd1, Oprm1) plasma membrane (Oprd1) cytoplasm (Oprd1)

Anatomy Link Frequency nucleus 1 Oprd1 (Rattus norvegicus) Oprm1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat orphanin 12 100.00 opioid receptor 3 100.00 Opioid 2 100.00 antagonist 2 65.12 narcan 4 48.00 excitatory amino acid 1 25.00 Glutamate 1 25.00

Disease Link Frequency Relevance Heat Pressure And Volume Under Development 3 73.20 Heart Rate Under Development 1 25.00 Pressure Volume 2 Under Development 1 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In this study, the role of the classic opioid mu receptor and the nociceptin/orphanin FQ receptor, a novel opioid receptor, in the nucleus tractus solitarii (NTS) in the regulation of cardiovascular activity was investigated and compared in chronically cannulated and freely moving conscious rats.

opioid receptor Spec (investigated) Regulation (role) of opioid mu receptor in nucleus associated with orphanin, opioid receptor and opioid

1) Confidence 0.03 Published 2005 Journal Neuroscience Section Abstract Doc Link 15857705 Disease Relevance 0.13 Pain Relevance 0.52

General Comments

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