INT126661

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Context Info
Confidence 0.65
First Reported 2005
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.59
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (RNF130) ligase activity (RNF130) cytoplasm (RNF130)
Anatomy Link Frequency
platelet 5
RNF130 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 5 80.24 Quite High
withdrawal 1 72.60 Quite High
Angina 11 50.00 Quite Low
antagonist 1 40.96 Quite Low
adenocard 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Adhesions 1 99.12 Very High Very High Very High
Cv General 3 Under Development 11 96.40 Very High Very High Very High
Hemorrhage 1 82.08 Quite High
Acute Coronary Syndrome 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The platelet tests uniformly revealed rebound activation by all platelet measures (at least twofold increase) while being especially high for ADP-, and collagen-induced aggregation, platelet/endothelial cell adhesion molecule-1 (PECAM-1), glycoprotein (GP)Ib, GPIIb/IIIa activity, P-selectin, protease activated receptor (PAR)-1 thrombin receptor (activated and intact epitopes), and thrombospondin expression.
Gene_expression (expression) of GP in platelet associated with adhesions
1) Confidence 0.65 Published 2006 Journal Int. J. Clin. Pract. Section Abstract Doc Link 16846403 Disease Relevance 0.18 Pain Relevance 0.11
There was no significantly different in platelet GP IIb/IIIa expression after the antiplatelet therapy in patients with unstable angina.


Neg (no) Gene_expression (expression) of GP in platelet
2) Confidence 0.58 Published 2005 Journal Pol. Merkur. Lekarski Section Body Doc Link 15859538 Disease Relevance 0.06 Pain Relevance 0
THE AIM: To estimate by flow cytometry GP IIb/IIIa expression on the platelets and platelet microparticles membrane.
Gene_expression (expression) of GP in platelet
3) Confidence 0.58 Published 2005 Journal Pol. Merkur. Lekarski Section Body Doc Link 15859538 Disease Relevance 0.10 Pain Relevance 0
In group B2- before treatment- the percentage of platelet expressing GP IIb/IIIa was lower (60.1%) than in the group B1.
Gene_expression (expressing) of GP in platelet
4) Confidence 0.58 Published 2005 Journal Pol. Merkur. Lekarski Section Body Doc Link 15859538 Disease Relevance 0.08 Pain Relevance 0
RESULTS: Patients with unstable angina in group B1 were by 12% higher expression of GP IIb/IIIa than control group (62.6 vs 55.1%).
Gene_expression (expression) of GP
5) Confidence 0.58 Published 2005 Journal Pol. Merkur. Lekarski Section Body Doc Link 15859538 Disease Relevance 0.08 Pain Relevance 0
THE AIM: To estimate by flow cytometry GP IIb/IIIa expression on the platelets and platelet microparticles membrane.
Gene_expression (expression) of GP in platelets
6) Confidence 0.20 Published 2005 Journal Pol. Merkur. Lekarski Section Body Doc Link 15859538 Disease Relevance 0.10 Pain Relevance 0

General Comments

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