INT126696

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2005
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.44
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (Crhr1, Crh) extracellular space (Crh) extracellular region (Crh)
plasma membrane (Crhr1) cytoplasm (Crh) signal transducer activity (Crhr1)
Anatomy Link Frequency
autonomic 2
Crhr1 (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 43 85.04 High High
isoflurane 2 72.56 Quite High
noradrenaline 3 57.76 Quite High
Central nervous system 2 25.60 Quite Low
anesthesia 2 25.00 Low Low
Nerve growth factor 28 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
cytokine 22 5.00 Very Low Very Low Very Low
agonist 22 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 17 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 54 100.00 Very High Very High Very High
Hypopituitarism 1 53.84 Quite High
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Cancer 22 5.00 Very Low Very Low Very Low
Targeted Disruption 22 5.00 Very Low Very Low Very Low
Pituitary Cancer 11 5.00 Very Low Very Low Very Low
Starvation 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Natriuresis 7 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Corticotropin-releasing factor (CRF) is released in response to various types of stressors and mediates endocrine, autonomic, immune, and behavioral responses to stress through interaction with CRF1 and CRF2 receptors.
CRF1 Binding (interaction) of Corticotropin-releasing factor in autonomic associated with stress
1) Confidence 0.50 Published 2005 Journal Brain Res. Section Abstract Doc Link 15862795 Disease Relevance 0.19 Pain Relevance 0.15
Corticotropin-releasing factor (CRF) is released in response to various types of stressors and mediates endocrine, autonomic, immune, and behavioral responses to stress through interaction with CRF1 and CRF2 receptors.
CRF1 Binding (interaction) of CRF in autonomic associated with stress
2) Confidence 0.50 Published 2005 Journal Brain Res. Section Abstract Doc Link 15862795 Disease Relevance 0.19 Pain Relevance 0.15
CRH and the different urocortin peptides bind with similar affinity to the CRH1-R, but the affinity of urocortin for the CRH2-R is much higher than that of CRH, whereas urocortin II has no affinity for CRH1-R (590).
CRH1-R Neg (no) Binding (affinity) of CRH
3) Confidence 0.01 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.05 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox