INT126794

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 3.26
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SRD5A1) small molecule metabolic process (SRD5A1) endoplasmic reticulum (SRD5A1)
cytoplasm (SRD5A1)
SRD5A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 31 100.00 Very High Very High Very High
Pain 1 60.92 Quite High
Onset of action 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Benign Prostatic Hypertrophy 112 99.74 Very High Very High Very High
Lower Urinary Tract Symptoms 57 99.66 Very High Very High Very High
Reprotox - General 2 12 93.20 High High
Reprotox - General 1 18 92.88 High High
Hypoactive Sexual Desire Disorder 4 90.80 High High
Aging 2 85.04 High High
Hematuria 7 63.80 Quite High
Pain 1 60.92 Quite High
Diuresis 8 57.60 Quite High
Pressure Volume 2 Under Development 4 52.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Current medical treatment of LUTS/BPH consists of monotherapy with alpha1-adrenoceptor (AR) antagonists, 5alpha-reductase inhibitors (RIs) or a combination of these.
5alpha-reductase Binding (monotherapy) of associated with benign prostatic hypertrophy, antagonist and lower urinary tract symptoms
1) Confidence 0.36 Published 2005 Journal BJU Int. Section Abstract Doc Link 15871731 Disease Relevance 2.90 Pain Relevance 0.19
The results of this study did not agree with 5-alpha-reductase inhibitor studies, perhaps because the average prostate size in the VA study was much smaller than in earlier trials.
5-alpha-reductase Neg (not) Binding (agree) of
2) Confidence 0.36 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778433 Disease Relevance 0.36 Pain Relevance 0.03

General Comments

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