INT126820

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Context Info
Confidence 0.26
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.85
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transporter activity (Slc22a6) plasma membrane (Slc22a6) protein complex (Slc22a6)
Slc22a6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 1 99.26 Very High Very High Very High
methotrexate 2 83.40 Quite High
vincristine 1 82.84 Quite High
cINOD 1 66.56 Quite High
aspirin 1 63.20 Quite High
Bile 1 47.28 Quite Low
anesthesia 1 25.00 Low Low
Morphine 5 5.00 Very Low Very Low Very Low
Patient controlled alalgesia 2 5.00 Very Low Very Low Very Low
Codeine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 1 99.26 Very High Very High Very High
Injury 92 99.02 Very High Very High Very High
Uremia 7 75.00 Quite High
Chronic Renal Failure 10 65.44 Quite High
INFLAMMATION 3 65.12 Quite High
Heart Rate Under Development 1 5.56 Low Low
Critical Illness 7 5.00 Very Low Very Low Very Low
Renal Disease 6 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Protein expression of rOat1 and rOat3, assessed by Western blot analysis, was decreased in 5/6 Nx rats.
Negative_regulation (decreased) of Gene_expression (expression) of rOat1
1) Confidence 0.26 Published 2005 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 15879000 Disease Relevance 0.27 Pain Relevance 0
Induction of AKI in ischemia-reperfusion rat models demonstrates decreased OAT1 and OAT3 mRNA as well as protein expression [34-36].
Negative_regulation (decreased) of Gene_expression (expression) of OAT1 associated with ischemia and injury
2) Confidence 0.06 Published 2008 Journal Crit Care Section Body Doc Link PMC2646335 Disease Relevance 0.58 Pain Relevance 0.26

General Comments

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