INT126827

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Context Info
Confidence 0.57
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.06
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgax)
Anatomy Link Frequency
blood 1
lung 1
T cells 1
Itgax (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 84.32 Quite High
anesthesia 3 78.92 Quite High
agonist 12 76.44 Quite High
palliative 1 71.16 Quite High
cytokine 11 64.28 Quite High
Inflammation 23 60.24 Quite High
isoflurane 4 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mastocytoma 1 96.64 Very High Very High Very High
Respiratory Syncytial Virus 66 93.32 High High
Infection 92 93.16 High High
Contact Dermatitis 1 89.96 High High
Pulmonary Disease 2 80.68 Quite High
Disease 25 76.64 Quite High
Graft Vs Host Disease 1 75.56 Quite High
Apoptosis 7 75.00 Quite High
Autoimmune Disease 1 74.68 Quite High
T-cell Lymphoma 1 72.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intravenous injection of these cells into naive mice caused inhibition of a hapten immune response, which was lost upon depletion of CD11c(+) cells but not T cells.
Negative_regulation (depletion) of CD11c in T cells
1) Confidence 0.57 Published 2005 Journal J. Immunol. Section Abstract Doc Link 15879089 Disease Relevance 0.46 Pain Relevance 0.15
In two separate experiments, expression levels of CD11c normalized to GAPDH were nearly equal in CD11c+ (relative expression = 1.05 ± 0.06, n = 4) and CD8+ (relative expression = 1.08 ± 0.03) cells from the lung following RSV infection.
Negative_regulation (levels) of CD11c in lung associated with infection and respiratory syncytial virus
2) Confidence 0.39 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.70 Pain Relevance 0
After 24 h, there was a decrease of AMs (CD11c+CD11b?
Negative_regulation (decrease) of CD11c
3) Confidence 0.27 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2762542 Disease Relevance 0.77 Pain Relevance 0.03
Experimental depletion of CD11c, but not CD14, cells from normal peripheral blood mononuclear cell (PBMC) similarly disabled Staphylococcus aureus Cowan 1 (SAC)-induced production of IL-12 p70 and IFNgamma.
Negative_regulation (depletion) of CD11c in blood
4) Confidence 0.03 Published 2005 Journal Shock Section Abstract Doc Link 15988317 Disease Relevance 0.12 Pain Relevance 0.18

General Comments

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