INT126886

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SP1, VEGFA) intracellular (SP1) DNA binding (SP1)
extracellular space (VEGFA) growth (VEGFA) extracellular region (VEGFA)
Anatomy Link Frequency
colon 3
SP1 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 2 99.44 Very High Very High Very High
cINOD 1 92.80 High High
COX-2 inhibitor 3 72.28 Quite High
Disease Link Frequency Relevance Heat
Colon Cancer 6 100.00 Very High Very High Very High
INFLAMMATION 1 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins.
Protein_catabolism (degradation) of Sp1 in colon Negative_regulation (decrease) of Gene_expression (expression) of vascular endothelial growth factor in colon associated with colon cancer and cox2
1) Confidence 0.03 Published 2005 Journal Mol. Pharmacol. Section Title Doc Link 15883203 Disease Relevance 0.49 Pain Relevance 0.26

General Comments

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