INT126932

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) mitochondrion (Slc8a2) extracellular region (Il10)
intracellular (Il10) plasma membrane (Slc8a2)
Anatomy Link Frequency
lamina 1
Slc8a2 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 2 61.80 Quite High
Apoptosis 1 50.00 Quite Low
Inflammatory Bowel Disease 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: Collectively, these data show that NCX-456 inhibits lamina propria T-helper type 1 function and stimulates the activity of interleukin 10- and transforming growth factor beta-secreting cells, thus restoring mucosal immune homeostasis and suppressing intestinal inflammation.


NCX-456 Positive_regulation (stimulates) of interleukin 10 in lamina
1) Confidence 0.09 Published 2005 Journal Gastroenterology Section Body Doc Link 15887108 Disease Relevance 0.06 Pain Relevance 0

General Comments

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