INT127040

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.72
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Alas1) biosynthetic process (Alas1) nucleus (Alas1)
transferase activity, transferring acyl groups (Alas1) cytoplasm (Alas1)
Alas1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 2 85.68 High High
Cannabinoid 3 84.84 Quite High
Pain 2 83.52 Quite High
Analgesic 1 72.68 Quite High
abdominal pain 2 70.00 Quite High
peripheral neuropathy 2 62.00 Quite High
Disease Link Frequency Relevance Heat
Porphyria 38 87.92 High High
Pain 2 81.60 Quite High
Hepatic Porphyrias 11 75.12 Quite High
Abdominal Pain 2 70.00 Quite High
Psychosis 1 68.48 Quite High
Peripheral Neuropathy 2 62.00 Quite High
Nicotine Addiction 1 57.72 Quite High
Disease 55 50.00 Quite Low
Syndrome 3 48.08 Quite Low
Diabetic Nephropathy 1 42.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, ALAS activity also decreased by 37%, suggesting that regulatory free heme pool was not modified.
Negative_regulation (decreased) of ALAS
1) Confidence 0.35 Published 2005 Journal Int. J. Biochem. Cell Biol. Section Abstract Doc Link 15896668 Disease Relevance 0.16 Pain Relevance 0.44
Glucose infusion may also suppress ALAS
Spec (may) Negative_regulation (suppress) of ALAS
2) Confidence 0.16 Published 2006 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC1559910 Disease Relevance 0.56 Pain Relevance 0.10

General Comments

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