INT127100

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Memo1, Nfkb1) nucleus (Memo1, Nfkb1) signal transduction (Nfkb1)
mitochondrion (Nfkb1) DNA binding (Nfkb1) nucleic acid binding transcription factor activity (Nfkb1)
Memo1 (Mus musculus)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 100.00 Very High Very High Very High
Antinociceptive 4 100.00 Very High Very High Very High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 100.00 Very High Very High Very High
Pressure And Volume Under Development 1 87.68 High High
Necrosis 1 61.08 Quite High
Cancer 1 60.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, the data demonstrate that MEMO has anti-inflammatory and antinociceptive activity, inhibiting iNOS, COX-2 and TNF-alpha expression by down-regulating NF-kappaB binding activity.
MEMO Negative_regulation (down-regulating) of NF-kappaB Binding (activity) of associated with inflammation and antinociceptive
1) Confidence 0.11 Published 2005 Journal J. Pharm. Pharmacol. Section Abstract Doc Link 15901350 Disease Relevance 0.57 Pain Relevance 0.36

General Comments

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