INT127115

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Context Info
Confidence 0.60
First Reported 2005
Last Reported 2005
Negated 0
Speculated 2
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 1.74
Pain Relevance 1.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smad2) DNA binding (Smad2) protein complex (Smad2)
transcription factor binding (Smad2) cytoplasm (Smad2)
Anatomy Link Frequency
frontal cortex 3
brain 2
hippocampus 1
Smad2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antidepressant 15 100.00 Very High Very High Very High
Hippocampus 12 99.52 Very High Very High Very High
fluoxetine 9 83.20 Quite High
Desipramine 3 76.72 Quite High
depression 3 58.32 Quite High
Eae 9 57.44 Quite High
antagonist 3 47.16 Quite Low
Disease Link Frequency Relevance Heat
Convulsion 9 100.00 Very High Very High Very High
Urological Neuroanatomy 9 98.88 Very High Very High Very High
Depression 3 58.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models.
Regulation (Regulation) of Phosphorylation (phosphorylation) of Smad2 in brain associated with antidepressant
1) Confidence 0.60 Published 2005 Journal J. Neurosci. Section Title Doc Link 15901772 Disease Relevance 0.52 Pain Relevance 0.53
The current study examines the influence of chronic electroconvulsive seizures (ECSs), as well as chemical antidepressants, on the expression of activin betaA and the phosphorylation of Smad2 in the rat hippocampus and frontal cortex.
Spec (examines) Regulation (influence) of Phosphorylation (phosphorylation) of Smad2 in frontal cortex associated with antidepressant, convulsion, urological neuroanatomy and hippocampus
2) Confidence 0.44 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 15901772 Disease Relevance 0.61 Pain Relevance 0.50
The current study examines the influence of chronic electroconvulsive seizures (ECSs), as well as chemical antidepressants, on the expression of activin betaA and the phosphorylation of Smad2 in the rat hippocampus and frontal cortex.
Spec (examines) Regulation (influence) of in hippocampus Phosphorylation (phosphorylation) of Smad2 in frontal cortex associated with antidepressant, convulsion, urological neuroanatomy and hippocampus
3) Confidence 0.15 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 15901772 Disease Relevance 0.61 Pain Relevance 0.50

General Comments

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