INT127124

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Context Info
Confidence 0.62
First Reported 2005
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.17
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Snca) mitochondrion (Snca) histone binding (Snca)
plasma membrane (Snca) cytoskeleton (Snca) nucleus (Snca)
Anatomy Link Frequency
brain 4
Snca (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 8 100.00 Very High Very High Very High
alcohol 10 98.32 Very High Very High Very High
opiate 8 98.00 Very High Very High Very High
addiction 4 96.08 Very High Very High Very High
Dopamine 2 94.84 High High
amygdala 9 92.40 High High
Nucleus accumbens 3 90.24 High High
Ventral tegmentum 3 88.40 High High
withdrawal 6 77.60 Quite High
projection neuron 4 44.84 Quite Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 3 97.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study investigated the influence of acute and chronic morphine administration on alpha-synuclein mRNA and protein expression in the brains of mice.
Spec (investigated) Regulation (influence) of Gene_expression (expression) of alpha-synuclein mRNA in brains associated with morphine
1) Confidence 0.62 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 15901780 Disease Relevance 0 Pain Relevance 0.84
Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice.
Regulation (Regulation) of Gene_expression (expression) of alpha-synuclein in brain associated with morphine
2) Confidence 0.62 Published 2005 Journal J. Neurosci. Section Title Doc Link 15901780 Disease Relevance 0 Pain Relevance 0.79
The aim of our study was to characterize the changes in alpha-synuclein expression after short-term abstinence from chronic alcohol drinking in mice.
Regulation (changes) of Gene_expression (expression) of alpha-synuclein associated with alcohol
3) Confidence 0.62 Published 2008 Journal Neuropharmacology Section Abstract Doc Link 18456291 Disease Relevance 0.17 Pain Relevance 0.40

General Comments

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