INT127262

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Context Info
Confidence 0.30
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) aging (Jun) nucleus (Jun)
DNA binding (Jun) transcription factor binding (Jun)
Anatomy Link Frequency
medulla 2
Jun (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventrolateral medulla 7 99.68 Very High Very High Very High
agonist 3 99.10 Very High Very High Very High
Clonidine 2 85.44 High High
medulla 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Hypotension 8 97.44 Very High Very High Very High
Hypertension 1 73.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, a similar hypotensive response (-37+/-3.5 mm Hg) caused by the selective imidazoline I1 receptor agonist rilmenidine (25 microg) was associated with reduction in c-jun mRNA expression in the rostral ventrolateral medulla, but not in the NTS.
Negative_regulation (reduction) of Transcription (expression) of c-jun in medulla associated with rostral ventrolateral medulla, hypotension and agonist
1) Confidence 0.30 Published 2005 Journal Eur. J. Pharmacol. Section Abstract Doc Link 15910806 Disease Relevance 0.52 Pain Relevance 0.61

General Comments

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