INT127273

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Context Info
Confidence 0.78
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 24
Total Number 29
Disease Relevance 9.53
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (AMH) extracellular space (AMH) aging (AMH)
extracellular region (AMH) cell-cell signaling (AMH) cytoplasm (AMH)
Anatomy Link Frequency
testis 4
Sertoli cells 3
follicle 2
node 1
ovarian follicles 1
AMH (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 42 99.96 Very High Very High Very High
nociceptor 2 99.48 Very High Very High Very High
Adelta 2 83.04 Quite High
dexamethasone 9 78.52 Quite High
Pain 42 60.00 Quite High
imagery 42 53.76 Quite High
Inflammation 17 44.32 Quite Low
fibrosis 7 43.64 Quite Low
Pain threshold 1 43.48 Quite Low
Inflammatory response 43 36.04 Quite Low
Disease Link Frequency Relevance Heat
Hypersensitivity 143 100.00 Very High Very High Very High
Cancer 954 99.96 Very High Very High Very High
Insulin Resistance 71 99.80 Very High Very High Very High
Polycystic Ovary Syndrome 522 98.80 Very High Very High Very High
Stomach Cancer 399 98.68 Very High Very High Very High
Esophageal Cancer 273 98.00 Very High Very High Very High
Liver Cancer 7 90.80 High High
Wound Infection 56 88.44 High High
Hyperinsulinism 10 87.92 High High
Congenital Anomalies 32 85.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The expression of AMH is localized in granulosa cells of primary, pre-antral and small antral follicles, suggesting an important role of AMH in human folliculogenesis [2].
Gene_expression (expression) of AMH in follicles
1) Confidence 0.78 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.15 Pain Relevance 0
Thus, is still unknown if the AMH excess in PCOS is secondary to the increase in pre-antral follicles number, or if an intrinsic increased AMH production by the granulosa cells is the cause of follicular arrest in PCOS.
Gene_expression (production) of AMH in granulosa cells associated with polycystic ovary syndrome
2) Confidence 0.68 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.76 Pain Relevance 0
The exploratory range of the human and monkey palm is enhanced by the abundance of low threshold, C-innervated heat receptors and the paucity of low threshold AMH type 2 heat nociceptors.
Gene_expression (abundance) of AMH in nociceptors associated with nociceptor
3) Confidence 0.67 Published 2005 Journal Pain Section Abstract Doc Link 15911150 Disease Relevance 0.13 Pain Relevance 0.23
In addition, a positive correlation was found between serum AMH levels and both follicle count and androgen levels [9].
Gene_expression (levels) of serum AMH in follicle
4) Confidence 0.67 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.50 Pain Relevance 0.03
In a prospective study [20], metformin acutely improved insulin resistance indexes and restored ovarian morphology, whereas no effect of the metformin-induced improved insulin-sensitivity and AMH levels was observed.
Gene_expression (levels) of AMH associated with insulin resistance
5) Confidence 0.60 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.48 Pain Relevance 0
Significant difference in intraovarian AMH levels was observed within PCOS patients who received metformin on the basis of clinical response, even if women ovulating under metformin maintained higher follicular AMH levels than healthy controls.
Gene_expression (levels) of AMH associated with polycystic ovary syndrome
6) Confidence 0.59 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.50 Pain Relevance 0.04
These correlations were successively confirmed [12], and a further relationship between AMH levels and insulin resistance indexes was demonstrated in untreated PCOS patients.
Gene_expression (levels) of AMH associated with polycystic ovary syndrome and insulin resistance
7) Confidence 0.59 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.42 Pain Relevance 0.03
Our data confirmed [27,28] that AMH levels were significantly higher in PCOS patients than in healthy controls.
Gene_expression (levels) of AMH associated with polycystic ovary syndrome
8) Confidence 0.59 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.54 Pain Relevance 0
Anti-Müllerian hormone (AMH) was expressed in presumptive Sertoli cells in the first trimester pre-graft control and expression was maintained in the cytoplasm of presumptive Sertoli cells after grafting, and was similar in localization to equivalent age-matched controls (Fig. 2).
Gene_expression (expressed) of Anti-M llerian hormone in Sertoli cells
9) Confidence 0.58 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0 Pain Relevance 0
Anti-Müllerian hormone (AMH) was expressed in presumptive Sertoli cells in the first trimester pre-graft control and expression was maintained in the cytoplasm of presumptive Sertoli cells after grafting, and was similar in localization to equivalent age-matched controls (Fig. 2).
Gene_expression (expressed) of AMH in Sertoli cells
10) Confidence 0.58 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0 Pain Relevance 0
Furthermore, in healthy subjects, DEHP concentration resulted in 10 differentially expressed genes, whereas 16 genes were differentially expressed in HDM-allergic subjects, among them anti-Müllerian hormone, which was significantly up-regulated after exposure to DEHPhigh house dust compared with exposure to DEHPlow house dust, and fibroblast growth factor 9, IL-6, and transforming growth factor-?
Gene_expression (expressed) of anti-M llerian hormone in fibroblast associated with hypersensitivity
11) Confidence 0.56 Published 2008 Journal Environ Health Perspect Section Abstract Doc Link PMC2592268 Disease Relevance 0.39 Pain Relevance 0
Significant differences (p < 0.05) were observed between Met-anov and Met-ov groups in AMH levels in the antral follicular fluid (Figure 1).
Gene_expression (levels) of AMH
12) Confidence 0.53 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.39 Pain Relevance 0
In both Met-anov and Met-ov groups, serum levels of LH, T, A, DHEAS, SHBG, fasting insulin, and AMH as well as the Ferriman-Gallwey score, FAI, GIR and HOMA, were significantly (p < 0.05) better than those in PCOS controls and significantly (p < 0.05) worse than those in non-PCOS controls (Table 1).
Gene_expression (levels) of AMH associated with polycystic ovary syndrome
13) Confidence 0.53 Published 2010 Journal J Ovarian Res Section Body Doc Link PMC2912910 Disease Relevance 0.26 Pain Relevance 0
AMH (lower panels) is expressed in first trimester pre-graft controls and localized to Sertoli cells within the newly formed seminiferous cords after grafting and in an equivalent age-matched control.
Gene_expression (expressed) of AMH in Sertoli cells
14) Confidence 0.50 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0 Pain Relevance 0
Figure 2Expression of AR and AMH in first-trimester human fetal testis xenografts.
Gene_expression (2Expression) of AMH in testis
15) Confidence 0.50 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0 Pain Relevance 0
In addition to these changes, weak expression of AMH in first trimester testes became stronger within the Sertoli cells after xenografting.
Gene_expression (expression) of AMH in testes
16) Confidence 0.50 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0.06 Pain Relevance 0
The present studies have shown that testis structure is maintained throughout the first and second trimester and that expression of functional markers of Sertoli (AMH), Leydig (3?
Gene_expression (expression) of AMH in testis
17) Confidence 0.39 Published 2010 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2939754 Disease Relevance 0.14 Pain Relevance 0
What kind of haptic input—or how many different levels of force—does a MIS surgeon actually receive?
Gene_expression (surgeon) of MIS
18) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2686803 Disease Relevance 0 Pain Relevance 0
Is an improvement in MIS outcome by adding haptics a stable trait, or does the effect wear off when a surgeon becomes more experienced in performing a certain MIS procedure?
Gene_expression (procedure) of MIS
19) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2686803 Disease Relevance 0 Pain Relevance 0
Is an improvement in MIS outcome by adding haptics a stable trait, or does the effect wear off when a surgeon becomes more experienced in performing a certain MIS procedure?
Gene_expression (outcome) of MIS
20) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2686803 Disease Relevance 0 Pain Relevance 0

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