INT127322

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1)
cytoplasm (Mapk1) cytosol (Mapk1) signal transduction (Mapk1)
Anatomy Link Frequency
hippocampus 1
Gpx3 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 2 95.96 Very High Very High Very High
Glutamate receptor 1 66.32 Quite High
antagonist 1 64.80 Quite High
tetrodotoxin 1 54.16 Quite High
Glutamate 1 25.36 Quite Low
Disease Link Frequency Relevance Heat
Hyperhomocysteinemia 2 92.88 High High
Neurological Disease 1 90.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here we show an activation of the extracellular signal-regulated kinases (ERK1 and ERK2) and the downstream nuclear targets Elk-1 and calcium/cAMP response element binding protein, in the hippocampus of cystathionine beta synthase deficient mice, a murine model of hyperhomocysteinemia.
extracellular Regulation (regulated) of ERK2 in hippocampus associated with hippocampus and hyperhomocysteinemia
1) Confidence 0.00 Published 2005 Journal Neuroscience Section Abstract Doc Link 15916860 Disease Relevance 0.27 Pain Relevance 0.21

General Comments

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