INT127363

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.50
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpb1) extracellular region (Cpb1) cellular_component (Cpb1)
biological_process (Cpb1)
Anatomy Link Frequency
neutrophils 2
shell 1
Cpb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory response 3 99.98 Very High Very High Very High
metalloproteinase 24 98.22 Very High Very High Very High
Inflammation 3 95.60 Very High Very High Very High
anesthesia 15 78.92 Quite High
cva 5 72.36 Quite High
imagery 14 68.56 Quite High
Inflammatory mediators 1 49.64 Quite Low
ischemia 12 10.32 Low Low
isoflurane 9 5.00 Very Low Very Low Very Low
Versed 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 99.80 Very High Very High Very High
Renal Disease 22 99.38 Very High Very High Very High
Leukocytosis 1 98.16 Very High Very High Very High
Hyperkalemia 4 96.64 Very High Very High Very High
Hypothermia 1 88.80 High High
Coronary Heart Disease 24 87.76 High High
Coma 1 85.60 High High
Injury 42 83.52 Quite High
Heart Rate Under Development 18 79.16 Quite High
Myocardial Reperfusion Injury 6 74.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As this work was entirely focused on developing the minimal invasive technique to accomplish CPB with cardioplegic arrest, we have not yet systematically investigated possible definite outcomes.
CPB Binding (accomplish) of
1) Confidence 0.32 Published 2008 Journal J Cardiothorac Surg Section Body Doc Link PMC2553064 Disease Relevance 0.26 Pain Relevance 0.03
As an indication, the disposable membrane for the oxygenator costs $65, the Plexiglas parts of the CPB system (venous reservoir, oxygenator shell) can be re-used after vigorous cleaning and sterilizing while the CPB tubing was discarded after each bypass run.
CPB Binding (indication) of in shell
2) Confidence 0.32 Published 2008 Journal J Cardiothorac Surg Section Body Doc Link PMC2553064 Disease Relevance 0.14 Pain Relevance 0.07
CD11b and CD66b expression on neutrophils increased at the initiation of CPB.
CPB Binding (initiation) of in neutrophils
3) Confidence 0.11 Published 2009 Journal Prz. Lek. Section Abstract Doc Link 20043576 Disease Relevance 0.17 Pain Relevance 0.25
The association between the lowest Do2 during CPB and HL is maintained within a multivariable model, and the predictivity of the lowest Do2 is confirmed by the ROC analysis.
CPB Binding (association) of
4) Confidence 0.04 Published 2006 Journal Crit Care Section Body Doc Link PMC1794481 Disease Relevance 0.31 Pain Relevance 0
The most important factors contributing to postoperative renal dysfunction after cardiac surgery are the use of CPB and other factors associated with using CPB [4].
CPB Binding (use) of associated with renal disease
5) Confidence 0.04 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2872858 Disease Relevance 0.66 Pain Relevance 0
Of the 31 preoperative and intraoperative variables subjected to univariate analysis, eight demonstrated a significant association with the occurrence of post-CPB LV dysfunction (Table 3).
CPB Binding (association) of
6) Confidence 0.03 Published 2010 Journal Crit Care Section Body Doc Link PMC2911741 Disease Relevance 0.27 Pain Relevance 0.03
This is probably due to the inclusion of parameters that are strongly affected by the nature of a cardiac operation with CPB.
CPB Binding (operation) of
7) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958846 Disease Relevance 0.59 Pain Relevance 0.05
The corresponding increase in neutrophil MMP-9 expression and production suggests that MMP-9 is derived primarily from neutrophils and may contribute to the inflammatory response associated with CPB.
CPB Binding (associated) of in neutrophils associated with inflammatory response and metalloproteinase
8) Confidence 0.02 Published 2005 Journal Anesth. Analg. Section Abstract Doc Link 15920174 Disease Relevance 0.10 Pain Relevance 0.72

General Comments

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