INT127430

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (VEGFA, TIMP1) extracellular space (VEGFA) aging (TIMP1)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
tendon 2
VEGFA (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 2 100.00 Very High Very High Very High
cytokine 2 98.84 Very High Very High Very High
Pain 3 91.52 High High
Glutamate 1 87.36 High High
Inflammation 1 81.56 Quite High
Disease Link Frequency Relevance Heat
Disease 2 95.00 High High
Pain 3 91.52 High High
INFLAMMATION 1 81.56 Quite High
Hypoxia 2 81.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since VEGF has the potential to stimulate the expression of matrix metalloproteinases and inhibits the expression of tissue inhibitors of matrix metalloproteinases (TIMP) in various cell types this cytokine might play a significant role in the pathogenetic processes during degenerative tendon disease.
VEGF Negative_regulation (inhibits) of Gene_expression (expression) of TIMP in tendon associated with metalloproteinase, disease and cytokine
1) Confidence 0.43 Published 2005 Journal Orthopade Section Abstract Doc Link 15926081 Disease Relevance 0.60 Pain Relevance 0.50

General Comments

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