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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tfap2d)
Anatomy Link Frequency
striatum 1
Tfap2d (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 1 99.68 Very High Very High Very High
addiction 1 92.76 High High
Ventral tegmentum 9 76.80 Quite High
GABAergic 1 75.00 Quite High
cocaine 5 62.40 Quite High
gABA 2 53.92 Quite High
opiate 1 31.36 Quite Low
Dopamine 2 25.52 Quite Low
withdrawal 1 25.00 Low Low
Norepinephrine uptake inhibitor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Stress 1 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transcription factor deltaFosB is induced in the nucleus accumbens and dorsal striatum by chronic exposure to several drugs of abuse, and increasing evidence supports the possibility that this induction is involved in the addiction process.
Positive_regulation (induced) of transcription factor deltaFosB in striatum associated with addiction and nucleus accumbens
1) Confidence 0.08 Published 2005 Journal Eur. J. Neurosci. Section Abstract Doc Link 15926929 Disease Relevance 0 Pain Relevance 0.33

General Comments

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