INT127440

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Context Info
Confidence 0.50
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cnr1) plasma membrane (Cnr1) response to stress (Cnr1)
signal transducer activity (Cnr1)
Cnr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 24 97.72 Very High Very High Very High
nud 14 93.60 High High
Endocannabinoid 13 91.84 High High
Hippocampus 1 88.04 High High
amygdala 1 87.52 High High
Opioid 1 84.04 Quite High
Cholecystokinin 1 83.72 Quite High
gABA 1 82.92 Quite High
Cannabinoid receptor 8 81.80 Quite High
Cannabinoid 25 78.40 Quite High
Disease Link Frequency Relevance Heat
Anxiety Disorder 7 99.96 Very High Very High Very High
Hypersensitivity 7 99.16 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

30 99.12 Very High Very High Very High
Depression 1 95.32 Very High Very High Very High
Dyspepsia 15 93.60 High High
Stress 58 93.36 High High
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Hyperalgesia 6 5.00 Very Low Very Low Very Low
Nociception 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pharmacological blockade of CB1 signaling increases severity of induced hypersensitivity
Positive_regulation (increases) of Negative_regulation (blockade) of CB1 associated with hypersensitivity
1) Confidence 0.50 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2912121 Disease Relevance 0.63 Pain Relevance 0.42
Pharmacological blockade of CB1 receptors induces anxiety in rats, and inhibition of anandamide metabolism produces anxiolytic-like effects.
Positive_regulation (induces) of Negative_regulation (blockade) of CB1 associated with anxiety disorder
2) Confidence 0.46 Published 2005 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 15927244 Disease Relevance 0.66 Pain Relevance 0.52

General Comments

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