INT127451

Context Info Confidence 0.20 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.40

mitochondrion (Cdk1) protein complex assembly (Cdk1) cytoplasm (Cdk1) mitosis (Cdk1) nucleus (Cdk1) cell cycle (Cdk1)

Cdk1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Analgesic 6 100.00 Inflammation 3 100.00

Disease Link Frequency Relevance Heat INFLAMMATION 3 100.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These compounds were screened for anti-inflammatory, analgesic and kinase (CDK1, CDK5 and GSK3) inhibition activities.

Positive_regulation (screened) of CDK1 associated with inflammation and analgesic

1) Confidence 0.20 Published 2005 Journal Bioorg. Med. Chem. Section Abstract Doc Link 15927836 Disease Relevance 0.27 Pain Relevance 0.40

General Comments

This test has worked.