INT127495

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Context Info
Confidence 0.48
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crtc2) cytoplasm (Crtc2)
Anatomy Link Frequency
caudate putamen 2
Crtc2 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 10 99.98 Very High Very High Very High
Hippocampus 2 98.64 Very High Very High Very High
mu opioid receptor 2 98.64 Very High Very High Very High
primary somatosensory cortex 2 79.76 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic treatment with morphine produced an increase in expression of CaMKIV and phosphorylated cAMP response element-binding protein (pCREB) in the CA3 region of the hippocampus, whereas a decrease in CaMKIV and pCREB expression was observed in the caudate putamen.
Gene_expression (produced) of phosphorylated cAMP response element-binding protein in caudate putamen associated with hippocampus and morphine
1) Confidence 0.48 Published 2005 Journal Neuroreport Section Abstract Doc Link 15931054 Disease Relevance 0 Pain Relevance 0.56
Chronic treatment with morphine produced an increase in expression of CaMKIV and phosphorylated cAMP response element-binding protein (pCREB) in the CA3 region of the hippocampus, whereas a decrease in CaMKIV and pCREB expression was observed in the caudate putamen.
Gene_expression (expression) of phosphorylated cAMP response element-binding protein in caudate putamen associated with hippocampus and morphine
2) Confidence 0.38 Published 2005 Journal Neuroreport Section Abstract Doc Link 15931054 Disease Relevance 0 Pain Relevance 0.56

General Comments

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