INT127498

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.54
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crtc2) cytoplasm (Crtc2)
Anatomy Link Frequency
caudate putamen 1
kidney 1
Crtc2 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 5 99.00 Very High Very High Very High
Hippocampus 1 98.64 Very High Very High Very High
mu opioid receptor 1 96.68 Very High Very High Very High
primary somatosensory cortex 1 79.76 Quite High
analgesia 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 83.12 Quite High
Hypertrophy 1 81.52 Quite High
Body Weight 7 67.52 Quite High
Weight Loss 1 64.00 Quite High
Diabetic Nephropathy 1 23.92 Low Low
Apoptosis 3 20.40 Low Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Insulin Resistance 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Diabetes Complications 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice lacking Rictor, a key element of the TORC2 complex shown to phosphorylate PKB/Akt on Ser473 [37], develop increased organ size, including kidney [38].
Phosphorylation (phosphorylate) of TORC2 in kidney
1) Confidence 0.54 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2910663 Disease Relevance 0.36 Pain Relevance 0
Chronic treatment with morphine produced an increase in expression of CaMKIV and phosphorylated cAMP response element-binding protein (pCREB) in the CA3 region of the hippocampus, whereas a decrease in CaMKIV and pCREB expression was observed in the caudate putamen.
Phosphorylation (phosphorylated) of phosphorylated cAMP response element-binding protein in caudate putamen associated with hippocampus and morphine
2) Confidence 0.51 Published 2005 Journal Neuroreport Section Abstract Doc Link 15931054 Disease Relevance 0 Pain Relevance 0.56

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox